Laboratory for Imaging Research and Informatics (IRIS) is affiliated with the Departments of Radiology within the School of Medicine (SOM), Computer Science within the College of Engineering and Applied Sciences (CEAS), Physics and Astronomy within the College of Arts and Science (CAS), and the Program in Biomedical Engineering (PIBE) of SUNY at Stony Brook (SUNY-SB). The laboratory conducts various researches which can be categorized broadly into applied science or relative narrowly into image science.

Applied science encompasses the middle ground between basic science and engineering technology, where a definite practical end is in mind, and where the approach may lead to new discoveries in basic science as well. Image science explores the nature via visualization. It can be basic science in exploring molecular sequences or cell functions in biology and physiology or in exploring the solar system in the universe. It can also be technology in detecting defects inside a matel or in detecting lesions in the brain and heart.

IRIS Laboratory conducts mainly medical imaging researches, specifically in information processing in medical imaging, within the image science domain.